Acute Hepatitis Virus - Evaluation - III

The Acute Hepatitis Virus Evaluation – III is a specialised blood test panel that helps investigate viral infections which can affect the liver and produce symptoms similar to acute hepatitis. It detects antibodies associated with Cytomegalovirus (CMV), Varicella Zoster Virus (VZV), Herpes Simplex Virus (HSV), and Epstein-Barr Virus (EBV). These infections can sometimes cause liver inflammation, particularly in children, pregnant women, or individuals with weakened immunity. The panel helps identify these less common viral causes when routine hepatitis tests are negative or inconclusive.

Who Should Get This Test Done?

This test is recommended for:

●     Individuals with symptoms of acute hepatitis but negative results for common hepatitis viruses.

●     Individuals with unexplained liver inflammation or persistently abnormal liver function tests.

●     Individuals experiencing fever, fatigue, jaundice, or enlarged lymph nodes along with signs of liver involvement.

●     Individuals with weakened immune systems who are at increased risk of viral infections.

●     Individuals whose healthcare provider suspects CMV, EBV, HSV, or VZV infection as a possible cause of hepatitis.

Why Consider This Test?

   This test:

●     Helps identify viral infections that may cause hepatitis-like illness.

●     Detects multiple viral antibodies through a single panel.

●     Supports diagnosis when routine hepatitis A, B, C, and E tests do not explain the symptoms.

●     Assists clinicians in narrowing down the underlying cause of liver inflammation.

●     Provides valuable information for planning further evaluation and appropriate patient management.

More Information

This panel detects CMV IgM, Varicella Zoster Virus IgM, Herpes Simplex Virus (HSV-1 & HSV-2) IgM, and Epstein-Barr Virus Early Antigen (EBV EA) IgG antibodies. These viruses are known to cause systemic infections and, in some cases, can involve the liver. Since their symptoms often overlap with those of acute viral hepatitis, testing for these infections can help establish the diagnosis, especially in patients with atypical presentations or when common hepatitis viruses have been ruled out.

 Other Names

●     Acute Hepatitis Evaluation – III

●     Viral Hepatitis Differential Panel – III

●     CMV, EBV, HSV & VZV Hepatitis Panel

●     Non-Hepatitis Viral Liver Infection Panel

●     Extended Acute Hepatitis Evaluation Panel