Anti-SSA/RO & SSB/LA IgG
This immunoblot test detects antibodies against SS-A (Ro) and SS-B (La) proteins, associated with autoimmune diseases like lupus and Sjogren’s syndrome. The test helps diagnose these conditions, which can cause dryness, joint pain, and skin rashes. It is also used for monitoring disease progression.
Overview of Anti-SSA/RO & SSB/LA IgG in Kozhikode
The Anti SSA/Ro & SSB/La IgG test detects IgG autoantibodies against the SSA/Ro and SSB/La ribonucleoproteins. These antibodies are most strongly associated with Sjögren’s syndrome, but are also found in Systemic Lupus Erythematosus (SLE), subacute cutaneous lupus, and neonatal lupus. Because IgG antibodies can cross the placenta, maternal Anti-SSA/Ro antibodies may increase the risk of neonatal lupus and congenital heart block in the baby. Testing both antibodies together provides a more complete autoimmune profile than testing either alone.
Who Should Get This Test Done?
This test is recommended for individuals who:
● Have persistent dry eyes and dry mouth suggestive of Sjögren’s syndrome.
● Have photosensitive skin rashes, joint pain, fatigue, or swollen salivary glands.
● Have an undifferentiated connective tissue disease requiring antibody characterization.
● Are pregnant or planning pregnancy with a known or suspected autoimmune condition.
● Have a newborn with features suggestive of neonatal lupus.
Why Consider This Test?
This test helps:
● Diagnose Sjögren’s syndrome, where Anti-SSA/Ro is a key serological marker.
● Support the diagnosis and classification of SLE and related autoimmune disorders.
● Identify patients at risk of neonatal lupus and congenital heart block during pregnancy.
● Predict specific disease manifestations, including photosensitive rashes and secondary Sjögren’s syndrome.
● Guide monitoring and treatment decisions through a more detailed autoimmune profile.
More Information
The SSA (Ro) and SSB (La) antibodies are among the most commonly requested autoantibodies during the evaluation of systemic autoimmune diseases. They are often tested alongside ANA, ENA profiles, and other autoimmune markers to provide a more complete assessment of immune system activity. This test forms an important part of the diagnostic workup for connective tissue diseases and is always interpreted in conjunction with the individual’s symptoms, medical history, physical examination, and other laboratory findings.
Other Names
● Anti-Ro and Anti-La Antibody Test
● SSA and SSB Antibody Test
● Sjögren’s Syndrome Antibody Test
● Anti-Ro/La IgG Panel
● Ro/La Autoantibody Test
● SSA/SSB Antibody Profile
● Anti SSA Antibody and Anti SSB Antibody Test
● Sjögren’s Syndrome Specific Antibody Panel
● Ro52 and La Antibody Test
Test included
- Anti Ss-a (ro) Igg
- Ss-b Abs Immunoblot
Doctor information
Test code
1007
CPT and Loinc codes
Department
- Autoimmune-ifa
Turn around time
Same Day
Performing locations
9 labs across India
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Serum | Yellow Vacutainer | .9 ML |
Specimen stability information
Serum
Package price
₹3860
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₹3860