Autoimmune Hepatitis Panel 2

The Autoimmune Hepatitis Panel is a specialized test panel used to evaluate autoimmune conditions affecting the liver. It includes Anti-Neutrophil Cytoplasmic Antibodies (ANCA) with p-ANCA, c-ANCA, and endpoint titre, along with Anti-Soluble Liver Antigen (Anti-SLA) antibodies. These markers help identify immune responses that may be associated with autoimmune liver diseases, particularly autoimmune hepatitis. The panel provides valuable information to support diagnosis and is typically interpreted alongside liver function tests, clinical findings, and other autoimmune markers.

Who Should Get This Test Done?

This test may be recommended for individuals who:

●     Have persistently abnormal liver function tests without an obvious cause.

●     Experience symptoms suggestive of autoimmune liver disease, such as fatigue, jaundice, or unexplained liver inflammation.

●     Need further evaluation for suspected autoimmune hepatitis.

●     Have a history of autoimmune disorders along with liver-related symptoms.

●     Require additional autoimmune antibody testing as advised by a hepatologist or healthcare provider.

Why Consider This Test?

Autoimmune hepatitis can be challenging to diagnose because its symptoms often resemble those of other liver conditions. The Autoimmune Hepatitis Panel combines important antibody tests that help identify immune-mediated liver damage and provides a more comprehensive assessment than a single marker alone. By evaluating both ANCA and Anti-SLA antibodies, the panel supports a more accurate diagnosis, helps distinguish autoimmune hepatitis from other liver disorders, and assists healthcare providers in planning appropriate clinical management.

More Information

This panel evaluates antibodies that are associated with autoimmune liver diseases. ANCA testing detects p-ANCA and c-ANCA patterns, while Anti-SLA is considered a highly specific marker for autoimmune hepatitis. Since no single test can confirm autoimmune hepatitis on its own, this panel is usually performed as part of a broader diagnostic workup that may also include liver enzyme tests, additional autoantibody panels, imaging studies, and, when required, liver biopsy findings.

Other Names

●     Autoimmune Hepatitis Antibody Panel

●     AIH Panel

●     Autoimmune Liver Disease Panel

●     Autoimmune Hepatitis Profile

●     ANCA and Anti-SLA Panel