HLA Duo Abdr & CDC & Flowcytometry Crossmatching

What is HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test?

• HLA Duo ABDR & CDC and Flow Cytometry Cross is a bundled pre-transplant compatibility workup combining donor–recipient HLA typing at A, B, and DR loci along with CDC crossmatch and flow crossmatch.

• ABDR refers to genotyping/antigen typing at HLA‑A, HLA‑B, and HLA‑DRB1. CDC crossmatch detects complement‑fixing antibodies and flow crossmatch detects lower‑titer IgG on T/B cells.

Why consider HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test ?

This panel is recommended in below clinical conditions -

• Detects different antibody risks

• Guides peri‑transplant management

• Orthogonal confirmation

Who should get this HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test in Thrissur?

• All solid‑organ transplant candidates and intended living donors during compatibility workup, particularly kidney recipients, where crossmatch status strongly correlates with rejection and graft survival.

• Sensitized recipients with prior transplants, transfusions, or pregnancies, where detecting any level of donor‑specific antibody is critical to planning or deferring transplantation.

More Information about HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test in Thrissur

Human leukocyte antigens are of three main types. Class I HLA antigens include HLA-A, B, and C molecules; class II, which includes HLA-DR, -DQ, and -DP loci, are on antigen-presenting cells; and class III contains genes for proteins that have immune functionality.

HLA class I typing is used to identify HLA-matched platelets for alloimmunized refractory patients and identify presence of HLA antigens associated with a number of diseases or as drug hypersensitivity markers class I HLA antigens include A, B, and C loci.