Prenatal Diagnosis - Amniotic Fluid, FISH

The Prenatal Diagnosis – Amniotic Fluid, FISH Test is a specialized genetic test performed on an amniotic fluid sample to rapidly detect certain chromosomal abnormalities in a developing fetus. It uses Fluorescence In Situ Hybridization (FISH) technology to identify changes in selected chromosomes that may be associated with genetic conditions. This test is often recommended when there is an increased risk of chromosomal abnormalities based on maternal age, prenatal screening results, ultrasound findings, or family history. It provides valuable information to support prenatal evaluation and clinical decision-making.

Who Should Get This Test Done?

This test may be recommended for individuals who:

●     Have abnormal findings on prenatal screening or ultrasound examinations.

●     Are at an increased risk of fetal chromosomal abnormalities due to maternal age or medical history.

●     Have a family history of genetic or chromosomal disorders requiring further prenatal evaluation.

●     Need additional genetic assessment following a healthcare provider’s recommendation.

●     Wish to investigate the possibility of specific chromosomal conditions during pregnancy after appropriate genetic counselling.

Why Consider This Test?

Pregnancy can sometimes raise questions that routine screening tests cannot fully answer. The Prenatal Diagnosis – Amniotic Fluid, FISH Test offers a focused genetic assessment by detecting selected chromosomal abnormalities in fetal cells. It serves as an important follow-up test when there is a higher likelihood of genetic conditions, helping healthcare providers and expectant parents gain additional information for informed pregnancy management and future care planning.

More Information

This test is performed on fetal cells obtained from an amniotic fluid sample and uses fluorescent DNA probes that bind to specific chromosomes. It is commonly used to evaluate chromosomes that are most frequently associated with major chromosomal disorders. While the FISH test provides targeted genetic information, it is often used alongside other prenatal diagnostic tests and clinical findings to achieve a comprehensive assessment of fetal health.

Other Names

●     Prenatal FISH Test – Amniotic Fluid

●     Amniotic Fluid FISH Analysis

●     Fetal Aneuploidy FISH Test

●     Fluorescence In Situ Hybridization (FISH), Amniotic Fluid

●     Prenatal Chromosomal FISH Test