Chimerism (Pre-Transplantation)
A small tissue biopsy is processed and examined to detect cellular abnormalities, cancer, or infections. The sample is analyzed under a microscope using various stains and techniques. It is commonly used to diagnose conditions like skin cancers, liver disease, and gastrointestinal disorders.
Overview of Chimerism (Pre-Transplantation) in Kochi
What is the purpose of this test?
Pre-transplant chimerism testing is used to establish baseline DNA profiles of the recipient and donor prior to hematopoietic stem cell transplantation (HSCT). It allows for accurate post-transplant monitoring of donor cell engraftment.
When is this test recommended?
It is performed prior to allogeneic HSCT to record genetic differences between donor and recipient, which are crucial for post-transplant follow-up.
How is the test conducted?
DNA is extracted from blood or buccal swabs of the donor and recipient, and STR (short tandem repeat) markers are analyzed using PCR-based methods.
What do the results indicate?
This is a preparatory test and does not yield diagnostic outcomes. The STR profiles generated are stored for comparison with post-transplant chimerism assays.
What are the next steps?
Post-transplant, repeat chimerism tests are performed to determine the proportion of donor vs. recipient cells, guiding the success of engraftment and need for therapeutic intervention.
Test included
- Name Of The Donor
- Chimerism Pre-transplantation
- Red Chilli
- Remarks / Recommendations
Doctor information
Test code
RD1452
CPT and Loinc codes
Department
- Advanced Molecular Diagnostics R&d
- Eia - Infectious Section
- Corporate
- Local Send Out
Turn around time
7 Working Days
Performing locations
1 labs across India
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 2 ML |
Specimen stability information
Edta Whole Blood, Edta Whole Blood
Test price
₹13020
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₹13020