Tacrolimus
A test to measure tacrolimus blood levels using Liquid Chromatography-Mass Spectrometry (LCMSMS), offering higher precision than other methods, particularly in organ transplant patients.
Overview of Tacrolimus in Kollam
What is Tacrolimus test?
Tacrolimus is an immunosuppressive drug that is used in preventing organ and tissue rejection in patients after transplantation. Tacrolimus test is a therapeutic drug monitoring (TDM) test that measures tacrolimus concentration—typically a trough sample taken just before the next dose—in EDTA whole blood to individualize dosing after transplantation and balance rejection prevention with toxicity risk.
Why consider Tacrolimus test?
Tacrolimus administration requires frequent and diligent monitoring by physicians to ensure proper dosage and to limit the potential for harmful adverse effects, which can include renal damage, neurotoxicity, and other serious adverse events.
It’s Important because
- Organ Rejection Prevention
- Toxicity Minimization
- Dosage Optimization
- Monitoring and Follow-up
- Detecting Potential Problems
- Individuals with Specific Symptoms
Who should get tested for Tacrolimus test?
- Solid‑organ transplant recipients (kidney, liver, heart, lung) receiving tacrolimus, especially in the early post‑transplant period and whenever medications or clinical status change.
- Patients with suspected graft dysfunction, rejection, or tacrolimus toxicity to correlate clinical findings with drug exposure.
- Recipients starting or stopping interacting agents or at risk for food–drug interactions (e.g., grapefruit, pomelo), where levels may shift unpredictably.
More information Tacrolimus test
Other Names – Tac, Tac Level, Tacrolimus, Tacrolimus level, Immunosuppressive Drug
Tacrolimus is an immunosuppressive agent used for prophylaxis of organ rejection post-transplant. Tacrolimus use is in combination with one or, most commonly, two other immunosuppressive medications. It has an application as an agent for the prevention or treatment of certain autoimmune diseases. In solid organ transplantation, it serves as the treatment of organ rejection in kidney, liver, and heart allogeneic transplants. There is also an off-label indication for the prevention of rejection in lung transplant patients.
Test included
- Tacrolimus
Doctor information
Test code
5950A
CPT and Loinc codes
Department
- Hplc & Lcmsms
Turn around time
Same Day
Performing locations
1 labs across India
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 3 ML |
| Heparin Whole Blood | Green Vacutainer |
Specimen stability information
Edta Whole Blood, Heparin Whole Blood
Collection instructions
1. Draw blood immediately before a schedule dose, 2. Require EDTA/Heparin Whole Blood to be collected directly in relevant vaccutainer only 3. Label with time of collection and administration of drug, preferably with drug dose. 4. Doctors name and contact details required 5. Clinical history is mandatory.6. Additional Information:Therapeutic range applies to trough specimens drawn immediately prior to morning dose.7. Storage 2-8ºC (7 WORKING DAYS)
Package price
₹4600
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