Cardiolipin Antibodies

The Cardiolipin Antibodies Profile (IgG, IgM), Serum is a blood test that measures IgG and IgM antibodies against cardiolipin, a type of phospholipid found in cell membranes. These antibodies are among the key markers used in the evaluation of Antiphospholipid Syndrome (APS), an autoimmune disorder associated with an increased tendency to form blood clots and certain pregnancy-related complications. The test is commonly performed as part of an autoimmune workup and is interpreted along with clinical findings and other antiphospholipid antibody tests.

Who should get this test done?

This test may be recommended for individuals who:

●     Have a history of unexplained blood clots in veins or arteries.

●     Experience recurrent pregnancy loss or other pregnancy-related complications suggestive of antiphospholipid syndrome.

●     Show symptoms or have a diagnosis of an autoimmune disorder, such as systemic lupus erythematosus (SLE).

●     Require evaluation for antiphospholipid antibodies as part of an autoimmune investigation.

●     Are advised by their healthcare provider to undergo testing for unexplained clotting disorders.

Why consider this test?

Unexplained blood clots or recurrent pregnancy complications may sometimes be linked to autoimmune antibodies that affect the body’s normal clotting mechanisms. The Cardiolipin Antibodies Profile measures both IgG and IgM antibodies, providing a more comprehensive assessment than a single antibody test. When combined with clinical evaluation and other laboratory investigations, this profile helps healthcare providers identify antiphospholipid syndrome and guide appropriate patient management.

More information

This profile evaluates two important classes of cardiolipin antibodies- IgG and IgM, which are commonly included in the laboratory assessment of suspected antiphospholipid syndrome. It is often requested alongside other antiphospholipid antibody tests, such as Beta-2 Glycoprotein I antibodies and Lupus Anticoagulant, to provide a more complete evaluation. The results should always be interpreted in the context of the individual’s medical history, symptoms, and other relevant laboratory findings.

Other names

●     Anticardiolipin Antibodies Profile (IgG & IgM)

●     Cardiolipin IgG and IgM Antibody Test

●     Anticardiolipin Antibody Panel

●     aCL Antibody Profile

●     Cardiolipin Antibody Panel, Serum