Myeloma Panel by FCM/Bone Marrow

What is Myeloma panel by flowcytometry test?

Myeloma panel by flowcytometry test is a multi‑color flow cytometry panel that uses antibodies against plasma cell and B‑cell markers (e.g., CD38, CD138, CD45, CD19, CD56, CD27, CD117, Kappa, and Lambda) to identify abnormal clonal plasma cells and separate them from normal counterparts. This comprehensive panel aids healthcare professionals in accurate disease detection, classification, and treatment planning for patients with multiple myeloma.

Why consider Myeloma panel by flowcytometry test?

Myeloma panel by flowcytometry test is considered for diagnosing multiple myeloma (MM), differentiating it from other conditions, determining its staging and prognosis, and monitoring the effectiveness of treatment, as it precisely identifies and quantifies abnormal plasma cells in the bone marrow and blood. This test is crucial because it provides detailed information about plasma cell characteristics, such as their surface protein expression, which helps distinguish neoplastic cells from normal ones and assesses their risk of progression.

• Diagnosing multiple myeloma
• Differentiating from other conditions
• Staging and prognosis
• Monitoring treatment
• Identifying circulating tumor cells

Who should get tested for Myeloma panel by flowcytometry test?

• Individuals with suspected or established multiple myeloma, smoldering myeloma, or related plasma cell dyscrasias undergoing diagnostic workup or response monitoring.

• Patients post‑treatment where sensitive detection of residual clonal plasma cells can guide prognosis and therapeutic decisions.

More Information about Myeloma panel by flowcytometry test

Multiple Myeloma (MM) belongs to a family of neoplasms involving clonal expansion of immunoglobulin secreting B-cells, often with bone marrow involvement, resulting in anemia and leukopenia.  Additionally, bone lesions are often seen.  This FISH panel is designed to detect the most common, and/or prognostically-significant abnormalities in Multiple Myeloma and related plasma cell neoplasms. Multiple myeloma arises from clonal plasma cells that accumulate in bone marrow and produce a monoclonal immunoglobulin (M-protein) or free light chains that can harm organs.

Other Names: Multiple Myeloma Flow Cytometry Panel; Plasma Cell Immunophenotyping by Flow Cytometry; Multiple myeloma diagnostic test