O6-Methylguanine Methyltransferase (MGMT) Promoter
This test assesses the methylation status of the MGMT promoter gene in tumors. It helps predict the response to chemotherapy, especially in glioblastoma and other cancers.
Overview of O6-Methylguanine Methyltransferase (MGMT) Promoter in Kottayam
What is the Methylguanine Methyltransferase (MGMT) Test?
The MGMT test evaluates the methylation status of the MGMT gene, which affects the tumor's response to alkylating agents in glioblastoma treatment.
Who should take this test?
Patients with newly diagnosed glioblastoma or other high-grade brain tumors should undergo this test to guide treatment decisions.
How is the test performed?
A tissue sample from the tumor is analyzed using methylation-specific PCR (MS-PCR) to assess MGMT gene methylation.
What do positive results indicate?
Positive results indicate MGMT promoter methylation, suggesting a better response to alkylating chemotherapy agents like temozolomide.
What happens after a positive result?
Treatment plans may include alkylating agents to enhance therapeutic outcomes.
Test included
- Mgmt Promoter Methylation
Doctor information
Test code
RD1469
CPT and Loinc codes
Department
- Advanced Molecular Diagnostics R&d
Turn around time
8 Working Days
Test run frequency
Every Day TIME - 10:00
Performing locations
2 labs across India
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 2 ML |
| Paraffin Block | Others | 1 ML |
| Plasma Cit.frozen | Blue Vacutainer | 1 ML |
Specimen stability information
Paraffin Block
Collection instructions
Site Of Biopsy & Clinical Details Mandatory If Tissue Recd
Test price
₹6825
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₹6825