Sickle Cell PCR

What is the Sickle Cell PCR Test?

This test uses polymerase chain reaction (PCR) to detect mutations in the HBB gene, which causes sickle cell anemia.


Who should get this test?

This test is recommended for:

Newborns as part of genetic screening.
Individuals with a family history of sickle cell disease.
Couples planning pregnancy in high-risk populations.



How is the test performed?

A blood or buccal swab sample is analyzed using PCR to detect HBB gene mutations.


What do the results indicate?


Positive for Mutation: Confirms sickle cell anemia or carrier status.
Negative Results: No evidence of sickle cell mutation.



Why is this test important?

Early diagnosis of sickle cell anemia helps initiate treatment and manage complications effectively.