DHEA-S (Dehydroepiandrosterone)

About the Test

The Dehydroepiandrosterone-S test measures the concentration of DHEA-S, a sulfated steroid hormone predominantly produced by the adrenal cortex. It serves as a precursor for androgen and estrogen synthesis and plays a significant role in endocrine balance.

DHEA-S is unique compared to other androgens due to its stability and long half-life, making it a reliable marker of adrenal androgen production. Unlike testosterone, which may fluctuate throughout the day, DHEA-S levels remain relatively constant, providing a consistent indicator of adrenal function. The Dehydroepiandrosterone-S test is widely used in evaluating disorders related to androgen excess or deficiency and is particularly helpful in differentiating adrenal from ovarian sources of androgen production.

Why Consider DHEA-S (Dehydroepiandrosterone) in Palakkad?

The Dehydroepiandrosterone-S test is essential in diagnosing conditions associated with abnormal androgen levels.

Elevated Levels May Indicate

• Adrenal tumors (benign or malignant)

• Congenital adrenal hyperplasia (CAH)

• Polycystic ovary syndrome (PCOS)

• Adrenal hyperactivity

Decreased Levels May Indicate

• Adrenal insufficiency

• Hypopituitarism

• Aging-related decline

Clinically, the Dehydroepiandrosterone-S test is particularly valuable when evaluating women with signs of androgen excess, as it helps determine whether the source is adrenal or ovarian.

Who Should Get DHEA-S (Dehydroepiandrosterone) Done in Palakkad?

Common Indications

• Women with:

  • Hirsutism

  • Acne

  • Irregular menstrual cycles

• Patients with suspected adrenal disorders

• Individuals with unexplained infertility

Additional Indications

• Children with:

  • Early puberty

  • Delayed sexual development

• Patients undergoing endocrine evaluation

More Information on DHEA-S (Dehydroepiandrosterone) in Palakkad

Advantages of the Test

• Minimal diurnal variation

• Stable biomarker of adrenal androgen production

• Useful in differential diagnosis

Clinical Interpretation

• Must be correlated with:

  • Testosterone levels

  • Cortisol levels

  • Clinical presentation

Important Considerations

• Age-related decline is normal

• Extremely high levels warrant imaging studies

• Often part of a broader hormonal panel