Fibrinogen

The Fibrinogen test measures the level of fibrinogen, a protein made by the liver that is essential for blood clotting and also rises during inflammation. Fibrinogen (Factor I) is converted into fibrin to form a blood clot. It is an acute-phase reactant, meaning levels increase with infection, inflammation, or tissue injury.

Why Consider Fibrinogen :

1. Unexplained bleeding or bruising

2. Suspected clotting disorders

3. Suspected excessive clotting (thrombosis)

4. Severe infection or sepsis

5. Liver disease evaluation

6. Monitoring critical illness

7. Cardiovascular risk assessment

When Fibrinogen is important

• Sudden bleeding with abnormal clotting tests

• Sepsis with falling platelet counts

• Suspected DIC

• Before high-risk surgery in bleeding disorders

Clinical Uses

Emergency & Critical Care

• Diagnosing and monitoring DIC

• Massive transfusion protocols

• Severe sepsis or trauma

Hematology

• Bleeding disorders

• Monitoring clotting factor replacement

Cardiovascular Risk

• High levels linked to:

• Heart attack

• Stroke