Factor V Activity

What is the Factor V Activity Citrated Plasma test?

This test measures the activity of Factor V, a clotting protein essential for normal blood coagulation. Abnormal Factor V activity can lead to bleeding disorders or thrombosis.


When is this test recommended?

It is performed for individuals with:

Unexplained bleeding or clotting episodes
A family history of Factor V deficiency or thrombophilia
Evaluation of liver function or Vitamin K deficiency



How is the test performed?

A blood sample is collected in a citrated tube to prevent clotting. The plasma is analyzed using a clotting assay to determine Factor V activity.


What do the results indicate?


Low Factor V activity: Suggests inherited or acquired Factor V deficiency, liver disease, or DIC.
Normal Factor V activity: Rules out Factor V deficiency.



Can medications affect the results?

Yes, anticoagulants and certain medications can influence Factor V activity, requiring careful interpretation.