Osmotic Fragility Test
Available viaHome Collection, Lab Visit
GenderMale & Female
Contains3 parametersEarliest reports inNext Day
PreparationNo preparation needed
Test details
About the test :
The Osmotic Fragility Test (OFT) measures how easily red blood cells (RBCs) burst (hemolyze) when exposed to varying concentrations of salt (hypotonic) solutions.
- It evaluates the stability and integrity of red blood cell membranes.
- Helps detect abnormal red blood cell shapes or fragility that can lead to hemolytic anemia.
Why the Test Is Ordered
1. Suspected hereditary red blood cell disorders
- Spherocytosis (RBCs are sphere-shaped and fragile)
- Elliptocytosis (RBCs are elliptical)
2. Unexplained anemia
- Hemolytic anemia (RBCs destroyed faster than they are made)
- Unexplained jaundice
3. Pre- or post-splenectomy evaluation
- To confirm diagnosis of hereditary spherocytosis before surgery
4. Investigate hemolysis from other causes
- Autoimmune hemolytic anemia
- Certain infections or medications
Clinical Significance
- Helps diagnose specific red blood cell membrane disorders
- Guides treatment decisions for hemolytic anemia
- Can indicate need for further genetic or hematology testing
Test included
Osmotic Fragility Test includes 3 parameters
- Red Cell Lysis Begins At
- Red Cell Lysis Ends At
- 50% Lysis At
Test code
5113
CPT and Loinc codes
Department
- Haemotology
Turn around time
Next Day
Test run frequency
Every Day TIME - 10:00 , 14:30
Performing locations
55 labs across India
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 3 ML |
| Heparin Whole Blood | Green Vacutainer | 3 ML |
Specimen stability information
Edta Whole Blood, Heparin Whole Blood
Osmotic Fragility Test
Package price
₹440
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