Lymphoma T(11;18)(API2Malti1) Translocation, BMPB

Available viaHome Collection
GenderMale & Female
Contains6 parameters
Earliest reports in8 Working Days
PreparationNo preparation needed

Overview of Lymphoma T(11;18)(API2Malti1) Translocation, BMPB in Kannur

What is Lymphoma t(11;18)(API2/MALT1) translocation test?

The Lymphoma t(11;18)(API2/MALT1) translocation test is a molecular cytogenetic test performed on bone marrow samples to detect a specific chromosomal translocation between chromosomes 11 and 18 — denoted as t(11;18)(q21;q21).This rearrangement leads to the fusion of the API2 (also known as BIRC3) gene on chromosome 11 with the MALT1 gene on chromosome 18, forming the API2-MALT1 fusion gene. t(11;18) is a hallmark genetic abnormality associated primarily with MALT lymphoma (mucosa-associated lymphoid tissue lymphoma) and occasionally seen in other low-grade B-cell lymphomas.

Lymphoma t(11;18)(API2/MALT1) translocation test is usually performed using Fluorescence In Situ Hybridization (FISH) method to confirm the presence of this translocation in bone marrow or tissue samples.

Why consider Lymphoma t(11;18)(API2/MALT1) translocation test in Kannur?

Lymphoma t(11;18)(API2/MALT1) translocation test can be considered for -

  • To confirm the diagnosis of MALT lymphoma, particularly in cases involving bone marrow or disseminated disease.

  • To differentiate MALT lymphoma from other types of B-cell lymphomas with similar morphology.

  • To help determine prognosis — patients with this translocation often show resistance to antibiotic therapy (H. pylori eradication) and may require systemic treatment.

  • To guide treatment planning and risk stratification.

  • To monitor disease involvement in bone marrow.

Who should get tested for Lymphoma t(11;18)(API2/MALT1) translocation test in Kannur?

Lymphoma t(11;18)(API2/MALT1) translocation test is generally recommended for:

  • Patients with suspected or confirmed MALT lymphoma involving the stomach, lungs, salivary glands, or other extranodal sites.

  • Individuals with lymphoma showing plasmacytic differentiation or low-grade B-cell features.

  • Cases where lymphoma has spread to bone marrow and confirmation of molecular subtype is required.

  • Patients not responding to H. pylori eradication therapy, suggesting possible t(11;18) positivity.

It is typically slow-growing and often arises in organs with chronic inflammation or infection.

Test included

Lymphoma T(11;18)(API2Malti1) Translocation, BMPB includes 6 parameters

  • Specimen
  • Clinical Indications

  • Total Number Of Cells Analysed
  • T(11;18)(api2/malt1)(q22;q21)
  • Normal
  • Interpretation

Test code

10344

CPT and Loinc codes

Department

  • Cytogenetics

Turn around time

8 Working Days

Performing locations

1 labs across India

Specimen vol. and vacutainer information

SpecimenVacutainerVolume
Others (fx)Others2 ML

Specimen stability information

Others (Fx)

Lymphoma T(11;18)(API2Malti1) Translocation, BMPB

₹5000

Health Checkup Category

Complete Care Packages

LYMPHOMA T(11;18)(API2MALTI1) TRANSLOCATION,BMPB Test in Other Cities

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